Version: 8.0.0
Date: Tue Jan 28 2025
wnt8a
Danio rerioZFIN:ZDB-GENE-980526-332
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

wnt8a

Species
Danio rerio
Symbol
wnt8a
Name
wingless-type MMTV integration site family, member 8a
Synonyms
  • etID309727.14
  • wnt8
Biotype
protein coding gene
Automated Description
Predicted to enable cytokine activity and frizzled binding activity. Involved in several processes, including axis specification; neural crest cell fate specification; and positive regulation of canonical Wnt signaling pathway. Acts upstream of or within with a positive effect on regulation of cell population proliferation. Acts upstream of or within several processes, including gastrulation; regionalization; and regulation of signal transduction. Is active in apoptotic body and cell surface. Is expressed in several structures, including germ ring; mesoderm; ovary; presumptive paraxial mesoderm; and unfertilized egg. Orthologous to human WNT8A (Wnt family member 8A).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12027
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          GRCz11
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          wnt8a molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            wnt8a role
            wnt8a genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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