Allele/Variant

Rarbtm1Vgi

Species
Mus musculus
Symbol
Rarbtm1Vgi
Category
allele
Allele of gene
Rarb
Transgenic Constructs
None
Synonyms
  • RARbeta-
Description
A genomic fragment containing sequences encoding the first zinc finger motif was replaced with a neomycin selection cassette. This region encodes an essential portion of the protein common to all encoded isoforms. Northern blot analysis on RNA derived from E13.5 homozygous embryos demonstrated that no detectable transcript is produced from this allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal excitatory postsynaptic potentialMGI
abnormal lung developmentMGI
abnormal pulmonary alveolar duct morphologyMGI
abnormal pulmonary alveolar sac morphologyMGI
abnormal pulmonary alveolar system morphologyMGI
abnormal respiratory functionMGI
abnormal spatial learningMGI
absent long-term depressionMGI
decreased body weightMGI
decreased pulmonary endothelial cell surfaceMGI
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Disease Associations

No data available