Allele/Variant

Or10a4tm2(Or7a40)Mom

Species
Mus musculus
Symbol
Or10a4tm2(Or7a40)Mom
Category
allele
Allele of gene
Or10a4
Transgenic Constructs
None
Synonyms
  • M12->P2-IRES-tau-lacZ
  • Or10a4tm2(Olfr19)Mom
Description
The coding region for Olfr19, modified by introduction of the hemagglutinin epitope tag between the second and third exon, was linked to the 5' end of an IRES-tau-lacZ-loxP-tk-neo-loxP expression cassette. Insertion of this construct replaced the entire translated region of the endogenous gene, and placed expression of the inserted sequences under control of the endogenous regulatory sequences. Transient expression of Cre recombinase in C57BL/6 blastocysts excised the thymidine kinase and neomycin sequences. This allele expresses a bicistronic mRNA encoding Olfr19 and a bovine tau-beta-galactosidase fusion protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations