Allele/Variant

Bub3tm1Khac

Species
Mus musculus
Symbol
Bub3tm1Khac
Category
allele
Allele of gene
Bub3
Transgenic Constructs
None
Synonyms
  • Bub3-
Description
Exons 2 and 3 were replaced with a lacZ-neomycin fusion gene lacking a promoter but possessing a splice acceptor site and an internal ribosome entry site (IRES). The authors believed that only the first 65 amino acids would be translated, producing a protein lacking three of the four WD40 domains as well as the protein-interacting kinetochore domain.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations