Allele/Variant

Ccna2tm1Sot

Species
Mus musculus
Symbol
Ccna2tm1Sot
Category
allele
Allele of gene
Ccna2
Transgenic Constructs
None
Synonyms
  • cyclin A2 (-)
Description
The entire coding region was replaced by a construct containing a lacZ gene with a nuclear localization signal linked to the 5' end and a neomycin gene under the control of thymidine kinase promoter. The endogenous promoter remained intact and controlled the expression of the inserted lacZ gene. Immunohistochemical analysis failed to detect cyclin A2 protein in morphologically abnormal embyros, which were presumed to be homozygous.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations