Allele/Variant

Tg(APPSWE)2576Kha

Species
Mus musculus
Symbol
Tg(APPSWE)2576Kha
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • APP695swe
  • APPK670N,M671L
Description
Overexpression of the human APP gene encoding the APP695.SWE mutation (K670N and M671L). The construct contained the APP gene fused to the hamster prion protein promoter. APP expression was measured in brains of transgenic mice by quantitation of immunoblots.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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