Allele/Variant

Tg(SOD1)3Cje

Species
Mus musculus
Symbol
Tg(SOD1)3Cje
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • 218/3
  • Cu/ZnSOD-Tg
Description
The entire human SOD1 sequence was used for the transgene. Seven copies of the transgene inserted into Chromosome 3 (J:18645). Northern blot analysis of brain and liver from transgenic animals showed expression of 0.9 kb and 0.7 kb transcripts similar to that in humans. Transgenic animals exhibited increased enzyme activity in nearly all tissues examined.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations