Allele/Variant

Fn1tm1Feb

Species
Mus musculus
Symbol
Fn1tm1Feb
Category
allele
Allele of gene
Fn1
Transgenic Constructs
None
Synonyms
  • EDAfl
Description
The endogenous EDA exon, which is subject to alternative splicing, was replaced with a floxed EDA exon modified with point mutations for optimization of both the 5' and the 3' splice sites. RNase protection and RT-PCR analysis confirmed constitutive EDA exon inclusion, showing the EDA exon to be included in 99-100% of transcript in all tissues of homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations