Allele/Variant

Tg(Mt1-RET)192Ina

Species
Mus musculus
Symbol
Tg(Mt1-RET)192Ina
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • Tg(Mt1-RET)192Num
  • Tg(Mt1-RFP/RET)192Num
Description
The transgene comprises the cDNA encoding the human ret proto-oncogene driven by the mouse metallothionein 1 promoter/enhancer and followed by a segment of the simian virus 40 (SV40) genome containing a splice signal, a polyadenylation signal and 3' flanking sequence. Northern blot analysis revealed high levels of transgene expression in tumors and varying levels in melanin-producing cells of other tissues in mice of this line, including skin, muscle and Harderian glands.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations