Allele/Variant

Gt(ROSA)26Sortm1(Akt1/EGFP)Glas

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm1(Akt1/EGFP)Glas
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
Synonyms
  • AktInd.Tg
  • c.a.Akt-EGFP
Description
The HSA-driven CreERt2 transgene was inserted in cis with a cassette containing a constitutively active form of Atk1 fused to EGFP (c.a.Akt-EGFP). Prior to the addition of tamoxifen, the HSA promoter drives transctiption of CreERt2, with absence of c.a.Akt-EGFP transcription. Upon the addition of tamoxifen, CreERt2 expression would drive its own excision, leaving the c.a.Akt-EGFP cassette downstream of the HSA promoter.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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