Allele/Variant

Grem1tm1Ecan

Species
Mus musculus
Symbol
Grem1tm1Ecan
Category
allele
Allele of gene
Grem1
Transgenic Constructs
None
Synonyms
  • Grem1flox
  • grem1loxP
Description
A loxP site was placed 335 bp upstream of exon 2. A second loxP site along with a Frt-flanked PGK-neomycin selection cassette was placed within exon 2, 550 bp downstream of the stop codon and deleting the final 66 bp of the exon. Expression of the targeted locus was unchanged in homozygous mice as determined by quantitative PCR.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations