Allele/Variant

Tg(Mt1-CBS*S466L)EB86Waku

Species
Mus musculus
Symbol
Tg(Mt1-CBS*S466L)EB86Waku
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • Tg-S466L
Description
The mouse promoter was used to drive zinc-inducible expression of the human cDNA with a point mutation that results in the amino acid substitution of lysine for serine at position 466. This mutation was identified in patients with homocystinuria. Three lines were created and line EB86 was selected as the representative line.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

No data available

Disease Associations

No data available