Allele/Variant

Tg(Pomc-cre)1Lowl

Species
Mus musculus
Symbol
Tg(Pomc-cre)1Lowl
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • Pomc-cre
  • Pomc-Cre(BAC2)
Description
A Pomc (pro-opiomelanocortin-alpha) (bacterial artificial chromosome; RPCI22-372J15) was used to generate mice expressing cre under the control of the Pomc promoter. The cre recombinase cDNA was inserted via homologous recombination into the first ATG transcription start site, ablating the first 30bp of the POMC coding sequence. This transgenic vector was introduced to FVB-derived embryos.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations