Allele/Variant

Trp53tm6Xu

Species
Mus musculus
Symbol
Trp53tm6Xu
Category
allele
Allele of gene
Trp53
Transgenic Constructs
None
Synonyms
  • p53Gln25Ser26
  • p53QS-Neo
Description
Leucine codon 25 (TTA) in exon 2 was changed to glutamine and tryptophan codon 26 (TTG) to serine (p.L25Q, p.W26S) and a loxP site flanked neomycin resistance gene cassette was inserted into intron 4. The neo cassette was removed through subsequent Cre-mediated recombination.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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