This is the minor variant of SNP rs13468707 (c.538G>A substitution leading to p.I180V) in exon 6 and codes for the mutant valine in place of the evolutionary conserved isoleucine. The C variant is found in the C57BL/6NJ, AKR/J, BALB/cJ, BALB/CBYJ, DBA/2J, FVB/NJ, NOD/LTJ ,NOD/ShiLtJ, NZO/HILtJ, and NZW/LacJ strains. This SNP is the equivalent of the well-documented human SNP rs2820949.