Allele/Variant

Aars1tm1Slac

Species
Mus musculus
Symbol
Aars1tm1Slac
Category
allele
Allele of gene
Aars1
Transgenic Constructs
None
Synonyms
  • Aarsstop
Description
Using a modified BAC RP24-359N5 for homologous recombination, a C723 modification in exon 15 was made via site-directed mutagenesis using an FRT-flanked neo and arabinose-induced FLP, which left behind one FRT site, and a loxP-flanked Stop-neo cassette was additionally inserted into intron 1, which resulted in this constitutively expressed null allele that can be cre-excised to yield an expressed C723A mutant allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
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