Allele/Variant

Akap11tm1.2Jsco

Species
Mus musculus
Symbol
Akap11tm1.2Jsco
Category
allele
Allele of gene
Akap11
Transgenic Constructs
None
Synonyms
  • AKAP220-KO
Description
A loxP site and FRT-flanked neomycin cassette are introduced into intron 5 followed by a loxP site placed in intron 7. Flp-mediated recombination removed the FRT-flanked neo cassette. Cre-mediated recombination removed exons 6 and 7. Western blot anaylsis on nine tissues confirmed that no protein was expressed in mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal kidney collecting duct morphology
MGI
decreased body length
MGI
decreased body size
MGI
decreased body weight
MGI
decreased locomotor activity
MGI
increased anxiety-related response
MGI
increased thigmotaxis
MGI
increased urine osmolality
MGI
short tibia
MGI
slow movement
MGI
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Disease Associations

No data available