Allele/Variant

Tg(Thy1-MAPT*L266V*G272V)13Ema

Species
Mus musculus
Symbol
Tg(Thy1-MAPT*L266V*G272V)13Ema
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • 3R Tau
Description
The human Tau containing three ~32 amino acid repeats bearing the L266V and G272V mutations associated with familial forms of Picks Disease is under the control of the neuronal mouse Thy1 promoter. Line 13 is a high expressing line and expresses 8 fold higher levels than line 2.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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