Allele/Variant

Zdhhc7tm1.2Lusc

Species
Mus musculus
Symbol
Zdhhc7tm1.2Lusc
Category
allele
Allele of gene
Zdhhc7
Transgenic Constructs
None
Synonyms
  • SERZ-beta KO
Description
A loxP site was inserted into intron 2 and a loxP site flanked neomycin resistance gene cassette into intron 4. The neo cassette was removed through cre-mediated recombination. Exons 3 and 4 were removed through subsequent cre-mediated recombination, resulting in a knock-out allele. The two exons encode the DHHC-CRD domain. RT-PCR, Western blots and immunohistochemistry confirmed absence of transcription and translation from this allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations