Allele/Variant

Tg(tetO-ERBB2*)26Kkw

Species
Mus musculus
Symbol
Tg(tetO-ERBB2*)26Kkw
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • tet-op-hHER2YVMA
Description
Seven direct repeats of the tetracycline-operator (tetO) sequence drive inducible expression of the human gene with in-frame AYVM insertion at residue M774 (YVMA used because M774insAYVM and A775insYVMA lead to identical amino acid changes). Two founders were established: 26 (low copy number, high expression levels) and 5B (high copy numbers, low expression levels).
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page