Allele/Variant

Cacna2d4em1(IMPC)J

Species
Mus musculus
Symbol
Cacna2d4em1(IMPC)J
Category
allele
Allele of gene
Cacna2d4
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences ATCAGATGTCAGATCCTCAA, TCTGACATCTGATCGTGATA, GCAGGGAGACTCTACTTACA and GGGGCTCAAACACAGTCAGA, which resulted in a 173 bp deletion beginning at Chromosome 6 positive strand position 119,238,969 bp and ending after 119,239,141 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000332836 (exon 2) and 91 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 83 and early truncation 8 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations