Allele/Variant

Tex22tm1.1Osb

Species
Mus musculus
Symbol
Tex22tm1.1Osb
Category
allele
Allele of gene
Tex22
Transgenic Constructs
None
Synonyms
None
Description
The L1L2_Pgk_P cassette was inserted at position 113051633 of Chromosome 12 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the PGK promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 113052817. The critical exon(s) is/are thus flanked by loxP sites. Cre mediated recombination without flp expression produced a reporter knockout mouse. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
no abnormal phenotype detectedMGI
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Disease Associations

No data available