Allele/Variant

Gnb1lem1(IMPC)Tcp

Species
Mus musculus
Symbol
Gnb1lem1(IMPC)Tcp
Category
allele
Allele of gene
Gnb1l
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of AGGCTTACCTAGCCGTCTTC targeting the 5' side and CACACAAGTACAATCTAGGG targeting the 3' side of a critical region (ENSMUSE00001445593 & ENSMUSE00001048285) along with a single-strand oligonucleotide encoding a Bxb1 attB site. This resulted in a 1,229-bp deletion of Chr16 from 18,362,769 to 18,363,997 (GRCm39) with an insertion of a Bxb1 attB sequence (GGCTTGTCGACGACGGCGGTCTCCGTCGTCAGGATCATACACCTT).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations