Allele/Variant

Mpc1tm1.2Mwol

Species
Mus musculus
Symbol
Mpc1tm1.2Mwol
Category
allele
Allele of gene
Mpc1
Transgenic Constructs
None
Synonyms
  • Mpc1D
Description
LoxP sites were inserted around exons 3-5 and an IRES-nls-eYFP, lox511 flanked stop signal, luciferase gene and FRT flanked selection cassette were inserted downstream of exon 5 via homologous recombination. Flp mediated recombination removed the selection cassette. Cre mediated recombination reomved exons 3-5 and the lox511 flanked stop signal creating a null allele and allowing expression of luciferase.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Disease Associations