Gene

Ldh

Species
Drosophila melanogaster
Symbol
Ldh
Name
Lactate dehydrogenase
Synonyms
  • CG10160
  • dLDH
Biotype
protein coding gene
Automated Description
Enables L-lactate dehydrogenase activity and alpha-ketoglutarate reductase activity. Involved in NADH oxidation; lactate catabolic process; and pyruvate metabolic process. Is active in cytosol. Is expressed in several structures, including adult heart; anterior endoderm anlage; imaginal disc; muscle cell; and organism subdivision. Used to study disease of metabolism. Orthologous to several human genes including LDHA (lactate dehydrogenase A); LDHAL6A (lactate dehydrogenase A like 6A); and LDHB (lactate dehydrogenase B).
FB Description
Lactate dehydrogenase (Ldh) encodes a protein involved in myoblast fusion and somatic muscle development.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43128
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            6.2595M6.2600M6.2605M6.2610M6.2615M6.2620M6.2625M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Ldh molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
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              Genetic Interactions

              Ldh role
              Ldh genetic perturbation
              Interactor gene
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              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
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