Gene

Vps25

Species
Drosophila melanogaster
Symbol
Vps25
Name
Vacuolar protein sorting 25
Synonyms
  • CG14750
  • dVps25
Biotype
protein coding gene
Automated Description
Predicted to enable protein homodimerization activity and structural molecule activity. Involved in several processes, including bicoid mRNA localization; imaginal disc-derived male genitalia morphogenesis; and maintenance of epithelial cell apical/basal polarity. Predicted to be part of ESCRT II complex. Is expressed in organism. Used to study cancer and carcinoma. Orthologous to human VPS25 (vacuolar protein sorting 25 homolog).
FB Description
Vacuolar protein sorting 25 (Vps25) encodes a member of the ESCRT-II complex, which sorts certain endocytosed receptors for degradation via the multivesicular body. As part of this complex, the product of Vps25 also has a role in bcd RNA localization.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13149
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
8.6255M8.6256M8.6257M8.6258M8.6259M8.6260M8.6261M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions