Predicted to enable acetyl-CoA C-acetyltransferase activity. Involved in determination of adult lifespan and fatty acid beta-oxidation. Located in mitochondrion. Is expressed in several structures, including adult head; adult heart; embryonic dorsal epidermis; germline cell; and gut section. Used to study lipid metabolism disorder; mitochondrial trifunctional protein deficiency; and steatotic liver disease. Human ortholog(s) of this gene implicated in mitochondrial metabolism disease and mitochondrial trifunctional protein deficiency 2. Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta).
FB Description
Mitochondrial trifunctional protein beta subunit (Mtpbeta) encodes a protein involved in fatty acid beta-oxidation.