Gene

Mtpβ

Species
Drosophila melanogaster
Symbol
Mtpβ
Name
Mitochondrial trifunctional protein beta subunit
Synonyms
  • ACoT
  • CG4581
Biotype
protein coding gene
Automated Description
Predicted to enable acetyl-CoA C-acetyltransferase activity. Involved in determination of adult lifespan and fatty acid beta-oxidation. Located in mitochondrion. Is expressed in several structures, including adult head; adult heart; embryonic dorsal epidermis; germline cell; and gut section. Used to study lipid metabolism disorder; mitochondrial trifunctional protein deficiency; and steatotic liver disease. Human ortholog(s) of this gene implicated in mitochondrial metabolism disease and mitochondrial trifunctional protein deficiency 2. Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta).
FB Description
Mitochondrial trifunctional protein beta subunit (Mtpbeta) encodes a protein involved in fatty acid beta-oxidation.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR18919
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
23.8668M23.8670M23.8672M23.8674M23.8676M23.8678M23.8680M23.8682M23.8684M23.8686M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions