Gene

cert

Species
Drosophila melanogaster
Symbol
cert
Name
ceramide transfer protein
Synonyms
  • BcDNA:GH07688
  • CERT
Biotype
protein coding gene
Automated Description
Enables ceramide binding activity and ceramide transfer activity. Involved in ceramide transport and sphingolipid metabolic process. Located in Golgi apparatus and endoplasmic reticulum. Used to study autosomal dominant intellectual developmental disorder 34. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 34. Orthologous to human CERT1 (ceramide transporter 1).
FB Description
ceramide transfer protein (cert) encodes a protein involved in determination of lifespan. Mutant flies present accelerated aging due to oxidative stress.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22902
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
8.283M8.284M8.285M8.286M8.287M8.288M8.289M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions