Gene

Saf6

Species
Drosophila melanogaster
Symbol
Saf6
Name
SAGA factor-like TAF6
Synonyms
  • CG3883
  • dSaf6
Biotype
protein coding gene
Automated Description
Enables protein heterodimerization activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of SAGA complex. Is expressed in organism.
FB Description
SAGA factor-like TAF6 (Saf6) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Saf6 replaces the product of mia within SAGA when the product of mia is restricted to the TFIID transcription complex. Notably, the product of Saf6 is essential for SAGA's co-activator function but does not impact either of its enzymatic activities.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10221
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
813.5k814.0k814.5k815.0k815.5k

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions