Gene

L2HGDH

Species
Drosophila melanogaster
Symbol
L2HGDH
Name
L-2-hydroxyglutarate dehydrogenase
Synonyms
  • CG10639
  • dL2HGDH
Biotype
protein coding gene
Automated Description
Enables 2-hydroxyglutarate dehydrogenase activity, forward reaction. Predicted to be located in mitochondrion. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in 2-hydroxyglutaric aciduria; L-2-hydroxyglutaric aciduria; cerebellar ataxia; hereditary spastic paraplegia; and visual epilepsy. Orthologous to human L2HGDH (L-2-hydroxyglutarate dehydrogenase).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43104
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
18.9720M18.9722M18.9724M18.9726M18.9728M18.9730M18.9732M18.9734M18.9736M18.9738M18.9740M18.9742M18.9744M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions