Gene

Phlpp

Species
Drosophila melanogaster
Symbol
Phlpp
Name
PH domain leucine-rich repeat protein phosphatase
Synonyms
  • CG10493
  • CT29458
Biotype
protein coding gene
Automated Description
Enables protein serine/threonine phosphatase activity. Involved in protein dephosphorylation and regulation of apoptotic process. Orthologous to human PHLPP1 (PH domain and leucine rich repeat protein phosphatase 1) and PHLPP2 (PH domain and leucine rich repeat protein phosphatase 2).
FB Description
PH domain leucine-rich repeat protein phosphatase (Phlpp) encodes an enzyme involved in apoptosis regulation and tumor growth suppression via dephosphorylation of the product of Akt.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45752
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
19.0595M19.0600M19.0605M19.0610M19.0615M19.0620M19.0625M19.0630M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions