Predicted to enable N6-threonylcarbomyladenosine methylthiotransferase activity. Predicted to be involved in tRNA methylthiolation. Located in endomembrane system. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in diabetes mellitus; diabetic retinopathy; gestational diabetes; and type 2 diabetes mellitus. Orthologous to human CDKAL1 (CDK5 regulatory subunit associated protein 1 like 1).