Gene

CD98hc

Species
Drosophila melanogaster
Symbol
CD98hc
Name
CD98 heavy chain
Synonyms
  • cd98hc
  • CD98hc1
Biotype
protein coding gene
Automated Description
Predicted to enable L-alanine transmembrane transporter activity; L-leucine transmembrane transporter activity; and aromatic amino acid transmembrane transporter activity. Involved in L-leucine import across plasma membrane. Located in cell cortex. Is expressed in several structures, including adult head; adult heart; embryonic/larval midgut primordium; ganglia; and gut section. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human SLC3A2 (solute carrier family 3 member 2).
FB Description
CD98 heavy chain (CD98hc) encodes a transporter involved in the transmembrane import of L-leucine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46673
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
7.9745M7.9750M7.9755M7.9760M7.9765M7.9770M7.9775M7.9780M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions