Gene

DCAF12

Species
Drosophila melanogaster
Symbol
DCAF12
Name
DDB1 and CUL4 associated factor 12
Synonyms
  • CG3313
  • dcaf12
Biotype
protein coding gene
Automated Description
Enables ubiquitin-like ligase-substrate adaptor activity. Involved in several processes, including autophagic cell death; evoked neurotransmitter secretion; and positive regulation of hippo signaling. Part of Cul4-RING E3 ubiquitin ligase complex. Is active in cytoplasm; nucleus; and presynapse. Is expressed in organism. Orthologous to human DCAF12 (DDB1 and CUL4 associated factor 12); DCAF12L1 (DDB1 and CUL4 associated factor 12 like 1); and DCAF12L2 (DDB1 and CUL4 associated factor 12 like 2).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19860
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
12.0150M12.0152M12.0154M12.0156M12.0158M12.0160M12.0162M12.0164M12.0166M12.0168M12.0170M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions