Involved in DNA synthesis involved in DNA repair; meiotic recombination checkpoint signaling; and response to camptothecin. Located in nucleus. Is expressed in organism. Used to study 46 XX gonadal dysgenesis.
FB Description
BRCA2, DNA repair associated (Brca2) encodes the ortholog of the human BRCA2 gene, which acts as a tumor suppressor. It is involved in double-strand break repair via homologous recombination. During meiosis in females it is involved in DNA repair and in the activation of a meiotic checkpoint. It co-immunoprecipitates with the checkpoint protein encoded by Rad9.