Gene

Brca2

Species
Drosophila melanogaster
Symbol
Brca2
Name
BRCA2, DNA repair associated
Synonyms
  • 30169
  • BcDNA:SD25109
Biotype
protein coding gene
Automated Description
Involved in DNA synthesis involved in DNA repair; meiotic recombination checkpoint signaling; and response to camptothecin. Located in nucleus. Is expressed in organism. Used to study 46 XX gonadal dysgenesis.
FB Description
BRCA2, DNA repair associated (Brca2) encodes the ortholog of the human BRCA2 gene, which acts as a tumor suppressor. It is involved in double-strand break repair via homologous recombination. During meiosis in females it is involved in DNA repair and in the activation of a meiotic checkpoint. It co-immunoprecipitates with the checkpoint protein encoded by Rad9.
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
24.5265M24.5270M24.5275M24.5280M24.5285M24.5290M24.5295M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions