Enables chromatin binding activity; nuclear receptor binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including negative regulation of DNA-templated transcription; positive regulation of mitotic cell cycle; and regulation of signal transduction. Located in chromosome and nucleus. Is expressed in several structures, including adult head; adult heart; antennal anlage; ganglia; and head epidermis primordium.
FB Description
putzig (pzg) encodes a nuclear protein that is involved in chromatin activation of replication related genes and signalling pathways including Notch, Ecdysone and JAK/STAT. It regulates growth, cell death and various developmental processes.