Gene

Vha16-1

Species
Drosophila melanogaster
Symbol
Vha16-1
Name
Vacuolar H[+] ATPase 16kD subunit 1
Synonyms
  • ATP6V0C
  • BcDNA:SD02875
Biotype
protein coding gene
Automated Description
Predicted to contribute to proton-transporting ATPase activity, rotational mechanism. Involved in vacuolar acidification. Located in fusome. Part of plasma membrane proton-transporting V-type ATPase complex. Is expressed in several structures, including anterior-posterior subdivision of organism; female germline cell; follicle cell; ganglia; and somatic muscle cell. Human ortholog(s) of this gene implicated in early-onset epilepsy 3 and thyroid gland carcinoma. Orthologous to human ATP6V0C (ATPase H+ transporting V0 subunit c).
FB Description
Vacuolar H[+] ATPase 16kD subunit 1 (Vha16-1) encodes the proteolipid component of V-ATPase, which is a multi-functional channel protein. It contributes to vesicle-membrane fusion, hydrophilic molecule transport and intercellular communication.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10263
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
6.626M6.627M6.628M6.629M6.630M6.631M6.632M6.633M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions