Enables 3',5'-cyclic-AMP phosphodiesterase activity and calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity. Involved in cAMP metabolic process; cGMP metabolic process; and male mating behavior. Located in extracellular space. Is expressed in several structures, including adult head; embryonic/larval crystal cell; embryonic/larval lymph gland; procrystal cell; and ventral midline of embryo. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 74. Orthologous to several human genes including PDE1C (phosphodiesterase 1C).