Gene

Glo1

Species
Drosophila melanogaster
Symbol
Glo1
Name
Glyoxalase 1
Synonyms
  • CG1707
  • glo1
Biotype
protein coding gene
Automated Description
Enables lactoylglutathione lyase activity. Involved in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione and regulation of insulin receptor signaling pathway. Predicted to be located in cytosol. Is expressed in adult head and organism. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in autistic disorder; diabetic retinopathy; end stage renal disease; type 2 diabetes mellitus; and vascular disease. Orthologous to human GLO1 (glyoxalase I).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10374
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
7.3936M7.3938M7.3940M7.3942M7.3944M7.3946M7.3948M7.3950M7.3952M7.3954M7.3956M7.3958M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions