Gene

TNS1

Species
Homo sapiens
Symbol
TNS1
Name
tensin 1
Synonyms
  • DKFZp586K0617
  • matrix-remodelling associated 6
Biotype
protein coding gene
Automated Description
Enables RNA binding activity. Predicted to be involved in fibroblast migration. Predicted to act upstream of or within cell-substrate junction assembly. Located in focal adhesion.
RGD Description
The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45734
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
217.80M217.82M217.84M217.86M217.88M217.90M217.92M217.94M217.96M217.98M218.00M218.02M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions