Gene

OR2A4

Species
Homo sapiens
Symbol
OR2A4
Name
olfactory receptor family 2 subfamily A member 4
Synonyms
  • olfactory receptor 2A10
  • olfactory receptor 2A4
Biotype
protein coding gene
Automated Description
Predicted to enable odorant binding activity and olfactory receptor activity. Involved in positive regulation of cytokinesis and regulation of actin cytoskeleton organization. Located in several cellular components, including Flemming body; cleavage furrow; and mitotic spindle.
RGD Description
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR26453
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
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    Disease Associations

    Cases where the expected disease association was NOT found
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    Alleles and Variants

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      Transgenic Alleles

      Species
      (carrying the transgene)
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        Models

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          Sequence Feature Viewer

          Genome location
          Assembly version
          GRCh38
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          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          OR2A4 molecule type
          Interactor gene
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            Genetic Interactions

            OR2A4 role
            OR2A4 genetic perturbation
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