Gene

TMEM97

Species
Homo sapiens
Symbol
TMEM97
Name
transmembrane protein 97
Synonyms
  • MAC30
  • meningioma-associated protein 30
Biotype
protein coding gene
Automated Description
Predicted to enable cholesterol binding activity and oxysterol binding activity. Involved in several processes, including cholesterol homeostasis; positive regulation of lipoprotein transport; and regulation of intracellular cholesterol transport. Located in several cellular components, including lysosome; nuclear membrane; and rough endoplasmic reticulum. Is active in endoplasmic reticulum.
RGD Description
TMEM97 is a conserved integral membrane protein that plays a role in controlling cellular cholesterol levels (Bartz et al., 2009 [PubMed 19583955]).[supplied by OMIM, Aug 2009]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR31204
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Mus musculusTmem9710 of 10YesYes  
Rattus norvegicusTmem9710 of 10YesYes  
Xenopus tropicalistmem979 of 9YesYes   
Danio reriotmem979 of 10YesYes  
Saccharomyces cerevisiaeEMA197 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogasterHsap\TMEM97UAS.Tag:HA
  • UASt
Showing 1 - 1 of 1 rows
per page

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
28.320M28.321M28.322M28.323M28.324M28.325M28.326M28.327M28.328M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions

No data available