Gene

DEFB106B

Species
Homo sapiens
Symbol
DEFB106B
Name
defensin beta 106B
Synonyms
  • BD-6
  • beta-defensin 106
Biotype
protein coding gene
Automated Description
Enables CCR2 chemokine receptor binding activity; heparin binding activity; and lipopolysaccharide binding activity. Involved in innate immune response. Located in membrane; microvesicle; and nucleus.
RGD Description
Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106B, represents the more telomeric copy. [provided by RefSeq, Oct 2014]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR20515
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
7.4830M7.4835M7.4840M7.4845M7.4850M7.4855M7.4860M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions