Gene

PGM3

Species
Homo sapiens
Symbol
PGM3
Name
phosphoglucomutase 3
Synonyms
  • acetylglucosamine phosphomutase
  • AGM1
Biotype
protein coding gene
Automated Description
Enables phosphoacetylglucosamine mutase activity. Involved in UDP-N-acetylglucosamine biosynthetic process; protein N-linked glycosylation; and protein O-linked glycosylation. Predicted to be located in cytosol. Implicated in immunodeficiency 23 and teratoma. Biomarker of cervical cancer.
RGD Description
This gene encodes a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45955
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
83.150M83.155M83.160M83.165M83.170M83.175M83.180M83.185M83.190M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions