Gene

Guca1b

Species
Mus musculus
Symbol
Guca1b
Name
guanylate cyclase activator 1B
Synonyms
  • BC018258
  • cDNA sequence BC018258
Biotype
protein coding gene
Automated Description
Enables calcium sensitive guanylate cyclase activator activity. Acts upstream of or within phototransduction; regulation of guanylate cyclase activity; and visual perception. Located in photoreceptor outer segment. Is expressed in retina outer nuclear layer. Human ortholog(s) of this gene implicated in retinitis pigmentosa 48. Orthologous to human GUCA1B (guanylate cyclase activator 1B).
MGI Description
PHENOTYPE: Mice homozygous for a null allele exhibit abnormal rod electrophysiology. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23055
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
47.697M47.698M47.699M47.700M47.701M47.702M47.703M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions