Gene

C1qtnf2

Species
Mus musculus
Symbol
C1qtnf2
Name
C1q and tumor necrosis factor related protein 2
Synonyms
  • 1810033K05Rik
  • Adih
Biotype
protein coding gene
Automated Description
Enables identical protein binding activity and signaling receptor binding activity. Involved in regulation of lipid metabolic process. Acts upstream of or within positive regulation of D-glucose import; positive regulation of MAPK cascade; and positive regulation of small molecule metabolic process. Located in extracellular space. Part of protein-containing complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and skeleton. Orthologous to human C1QTNF2 (C1q and TNF related 2).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele show decreased body weight, reduced adiposity, increased metabolic rate and energy expenditure, enhanced adipose tissue lipolysis, and altered hepatic and plasma lipid profiles. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15427
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
43.366M43.368M43.370M43.372M43.374M43.376M43.378M43.380M43.382M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions