Gene

Dapl1

Species
Mus musculus
Symbol
Dapl1
Name
death associated protein-like 1
Synonyms
  • 2310032F03Rik
  • EEDA
Biotype
protein coding gene
Automated Description
Predicted to enable ribosome binding activity; translation initiation factor binding activity; and translation repressor activity. Involved in negative regulation of CD8-positive, alpha-beta T cell activation. Acts upstream of or within cell population proliferation and gene expression. Is active in nucleus. Is expressed in 1-cell stage embryo; cap mesenchyme; eye; integumental system; and tongue epithelium. Orthologous to human DAPL1 (death associated protein like 1).
MGI Description
PHENOTYPE: Mice homozygous for a null allele exhibit increased proliferation of retinal pigment epithelial cells forming multiple layers. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13177
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
59.316M59.318M59.320M59.322M59.324M59.326M59.328M59.330M59.332M59.334M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions