Enables sulfotransferase activity. Acts upstream of or within sulfate assimilation. Predicted to be located in cytosol and intracellular membrane-bounded organelle. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 14. Orthologous to human SULT2B1 (sulfotransferase family 2B member 1).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele lack cholesterol sulfate in the dermis but otherwise appear to have normal lipid metabolism. [provided by MGI curators]