Involved in binding activity of sperm to zona pellucida; flagellated sperm motility; and regulation of flagellated sperm motility. Located in acrosomal membrane; extracellular region; and plasma membrane. Is expressed in genitourinary system and submandibular gland. Orthologous to human TEX101 (testis expressed 101).
MGI Description
PHENOTYPE: Male mice homozygous for a knockout allele of this marker are infertile due to the failure of sperm to migrate into the oviduct. [provided by MGI curators]