Gene

Traf3ip3

Species
Mus musculus
Symbol
Traf3ip3
Name
TRAF3 interacting protein 3
Synonyms
  • 6030423D04Rik
  • AI115021
Biotype
protein coding gene
Automated Description
Predicted to enable protein-macromolecule adaptor activity and zf-TRAF domain binding activity. Acts upstream of or within several processes, including antiviral innate immune response; cellular response to cytokine stimulus; and positive regulation of type I interferon production. Predicted to be located in Golgi membrane; endoplasmic reticulum membrane; and mitochondrial membrane. Predicted to be active in mitochondrion. Is expressed in several structures, including cerebral cortex; eye; foregut; limb segment; and vertebral axis musculature. Orthologous to human TRAF3IP3 (TRAF3 interacting protein 3).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired single positive thymocyte development and increased gamma-delta T cell numbers. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15715
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
192.860M192.865M192.870M192.875M192.880M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions